Table 4.

Baseline demographics.

	DOACS (n = 3,044)	WARFARIN (n = 31,472)	RR (95% CI)	P -value
Age mean (SD)	70.55 (4.17)	70.32 (4.6)	0.70 [−1.13, 2.53]	P = 0.45
Female Sex	1,347 (44.25%)	13,812 (43.88%)	1.04 [0.92, 1.17]	P = 0.54
CHA2 DS2 -VASc score mean (SD)	3.91 (1.35)	4.28 (1.15)	−0.07 [−0.20, 0.06]	P = 0.28
Comorbid conditions (%)
Stroke/TIA
N patients	3,044	31,472
N events	883 (29%)	8708 (27.66%)	1.00 [0.94, 1.06]	P = 1.00
Heart failure
N patients	2,962	31,400
N events	1,979 (66.8%)	19,705 (62.75%)	0.96 [0.71, 1.28]	P = 0.76
Hypertension
N patients	2,916	31,356
N events	2,826 (96.9%)	30,313 (96.67%)	0.99 [0.93, 1.05]	P = 0.75
Diabetes mellitus
N patients	2,962	31,400
N events	2,177 (73.49%)	23,102 (73.57%)	1.01 [0.99, 1.03]	P = 0.43

DOACS, Direct oral anticoagulants; SD, Standard deviation; TIA, transient ischemic attack; RR, risk ratio; CI, confidence interval.