Skip to main content
. 2022 Apr 7;14(2):245–270. doi: 10.1016/j.jcmgh.2022.04.002

Figure 14.

Figure 14

TM9SF4 expression was down-regulated in human UC and mouse experimental colitis. (A) Tissue biopsy specimens from normal and inflamed regions of colons from patients with UC were collected. Levels of TM9SF4 from case 1 to case 7 were determined by Western blot. Representative (B) images and (C) data summary of TM9SF4 immunostaining in normal (n = 25) and inflamed (n = 15) regions of colons from UC patients. Scale bar: 100 μm. Representative (D) images and (E) data summary of TM9SF4 staining in colons from UC patients with low Mayo scores (n = 9) and high Mayo scores (n = 6). Scale bar: 100 μm. Representative immunostaining (F) images and (G) data summary of GRP78 and CHOP in normal (n = 15) and inflamed (n = 15) regions of colons from UC patients. Scale bars: 100 μm. Representative TM9SF4 immunohistochemistry staining (H) images and (I) data summary of colons from WT mice with or without 2% DSS treatment. Scale bar: 100 μm. Means ± SEM. ∗∗P < .01, ∗∗∗P < .001. DAB, 3,3′-Diaminobenzidine; GAPDH, glyceraldehyde-3-phosphate dehydrogenase.