Figure 4.
4-PBA alleviated ER stress in vitro. 4-APB reversed the effect of TM9SF4 knockdown on (A) IL1β and IL6 production, (B) GRP78 increase, (B) caspase 3 activity increase, and (C) ROS production in HCECs (n = 3). Scale bar: 100 μm. Means ± SEM. ∗P < .05, ∗∗P < .01, and ∗∗∗P < .001. SCR, scrambled control.