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. 2022 May 20;298(7):102059. doi: 10.1016/j.jbc.2022.102059

Figure 2.

Figure 2

SilencingRORα expression promotes EMT.A and B, transwell invasion analysis of control and RORα-silenced MCF10A cells; n = 3. Bar represents 20 μm. ∗∗p < 0.01. C–E, single-cell migration analysis in control and RORα-silenced MCF10A cells. Migration of RORα1 silenced cells was significantly reduced compared with the control cells; n = 100. ∗p < 0.01. F and G, wound healing assay shows the migration of control and RORα-silenced MCF10A cells. Bar represents 20 μm. n = 3. ∗p < 0.01. EMT, epithelial–mesenchymal transition; RORα, retinoid orphan nuclear receptor alpha.