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. 2022 May 23;298(7):102063. doi: 10.1016/j.jbc.2022.102063

Table 2.

Prediction of physicochemical properties of compounds 6a–6x, Z, and SMART

Compound cLogP PSA HBA HBD
6a 1.90 98.86 8 1
6b 2.51 98.86 8 1
6c 2.51 98.86 8 1
6d 2.34 98.86 8 1
6e 1.85 144.78 10 1
6f 2.06 98.86 8 1
6g 2.25 98.86 8 1
6h 2.22 98.86 8 1
6i 2.57 98.86 8 1
6j 2.74 98.86 8 1
6k 2.55 98.86 8 1
6l 2.57 98.86 8 1
6m 2.36 98.86 8 1
6n 1.95 108.19 9 1
6o 3.14 98.86 8 1
6p 2.65 98.86 8 1
6q 2.62 98.86 8 1
6r 2.22 108.19 9 1
6s 2.12 144.78 10 1
6t 2.33 98.86 8 1
6u 2.49 98.86 8 1
6v 1.76 108.19 9 1
6w 1.66 144.78 10 1
6x 1.86 98.86 8 1
Z 2.90 75.49 6 0
SMART 4.11 57.66 5 0

cLogP, calculated logarithm of octanol–water partition coefficient; HBA, hydrogen-bond acceptor atoms; HBD, hydrogen-bond donor atoms; PSA, polar surface area.