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. 2022 Jun 9;9:855787. doi: 10.3389/fmed.2022.855787

TABLE 1.

Study population characteristics (N = 82).

EC
n = 20
HHC
n = 17
PAR-NC
n = 26
CAR-TP
n = 19
p-value
Age, years, mean (SD) 29.5 (12.3) 42.8 (16.7) 43.9 (16.9) 58.6 (13.0) <0.0001a
Sex, n (%)
Male 7 (35) 9 (52.9) 17 (65.4) 15 (78.9) 0.03b
Female 13 (65) 8 (47.1) 9 (34.6) 4 (21.1)
Therapeutic scheme, n (%)
PB 2 (7.7) 1 (5.3) 0.009b,c
MB 24 (92.3) 10 (52.6)
DDS 0 (0) 5 (26.3)
Clinical form, n (%)
I 1 (3.8)
TT 1 (3.8)
BT 1 (3.8)
BB 13 (50)
BL 3 (11.6)
LL 7 (27)
PCR-RLEP test, n (%)
Positive 15 (57.7) 11 (57.9) 0.09b,d
Negative 3 (11.5) 8 (42.1)
Ct, mean (SD) 28⋅07 (1.065) 30⋅96 (0.330) 0.03e

aComparison of four groups using the Kruskal–Wallis test.

bComparison of the four and two groups using the chi-square test.

cData not available for three volunteers in the CAR-TP group.

dData not available for eight volunteers in the PAR-HD group.

eComparison of qPCR-RLEP positivity between PAR-NC and CAR-TP cells using the t-test.

EC, endemic controls; HHC, household contacts of HD patients; PAR-NC, new cases of HD in Parnaíba; CAR-TP, patients treated in Colony Carpina; SD, standard deviation; PB, paucibacillary; MB, multibacillary; I, indeterminate; TT, tuberculoid; BT, borderline-tuberculoid; BB, borderline-borderline; BL, borderline-lepromatous; LL, lepromatous; PCR-RLEP, quantitative polymerase chain reaction-specific repetitive element; Ct, cycle threshold; IQR, interquartile range.