TABLE 1.
EC n = 20 |
HHC n = 17 |
PAR-NC n = 26 |
CAR-TP n = 19 |
p-value | |
Age, years, mean (SD) | 29.5 (12.3) | 42.8 (16.7) | 43.9 (16.9) | 58.6 (13.0) | <0.0001a |
Sex, n (%) | |||||
Male | 7 (35) | 9 (52.9) | 17 (65.4) | 15 (78.9) | 0.03b |
Female | 13 (65) | 8 (47.1) | 9 (34.6) | 4 (21.1) | |
Therapeutic scheme, n (%) | |||||
PB | − | − | 2 (7.7) | 1 (5.3) | 0.009b,c |
MB | − | − | 24 (92.3) | 10 (52.6) | |
DDS | − | − | 0 (0) | 5 (26.3) | |
Clinical form, n (%) | |||||
I | − | − | 1 (3.8) | − | |
TT | − | − | 1 (3.8) | − | |
BT | − | − | 1 (3.8) | − | |
BB | − | − | 13 (50) | − | |
BL | − | − | 3 (11.6) | − | |
LL | − | − | 7 (27) | − | |
PCR-RLEP test, n (%) | |||||
Positive | − | − | 15 (57.7) | 11 (57.9) | 0.09b,d |
Negative | − | − | 3 (11.5) | 8 (42.1) | |
Ct, mean (SD) | − | − | 28⋅07 (1.065) | 30⋅96 (0.330) | 0.03e |
aComparison of four groups using the Kruskal–Wallis test.
bComparison of the four and two groups using the chi-square test.
cData not available for three volunteers in the CAR-TP group.
dData not available for eight volunteers in the PAR-HD group.
eComparison of qPCR-RLEP positivity between PAR-NC and CAR-TP cells using the t-test.
EC, endemic controls; HHC, household contacts of HD patients; PAR-NC, new cases of HD in Parnaíba; CAR-TP, patients treated in Colony Carpina; SD, standard deviation; PB, paucibacillary; MB, multibacillary; I, indeterminate; TT, tuberculoid; BT, borderline-tuberculoid; BB, borderline-borderline; BL, borderline-lepromatous; LL, lepromatous; PCR-RLEP, quantitative polymerase chain reaction-specific repetitive element; Ct, cycle threshold; IQR, interquartile range.