Table 3.
Brainnetome atlas regions for which the SDI values were significantly associated with the severity of positive psychotic symptoms in 22q11DS. The first column indicates the region’s location in the brain, while the second column indicates the brain region’s name (BA = Brodmann Area) with the correspondent region’s IDs of the Brainntetome atlas (third column). The brain salience value associated to the correspondent region is also listed (fourth column): positive values indicate that deletion carriers with more severe psychotic symptoms present weaker FSD, while negative values indicate they present stronger FSD.
|
Higher FSD in deletion carriers experiencing positive psychotic symptoms | |||
|---|---|---|---|
| Region’s Location | Region's name (hemisphere) | Region's ID | Brain salience |
| Superior Temporal Gyrus | medial BA 38 (L) | 69 | −2.44 |
| BA 41/42 (R) | 72 | −2.48 | |
| TE1.0 and TE1.2 (R) | 74 | −2.34 | |
| rostral BA 22 (R) | 80 | −2.36 | |
| rostral BA 21 (R) | 84 | −2.46 | |
| Inferior Temporal Gyrus | rostral BA 20 (L) | 93 | −3.32 |
| intermediate lateral BA 20 (L) | 95 | −2.47 | |
| intermediate lateral BA 20 (R) | 96 | −3.09 | |
| rostroventral BA 20 (L) | 103 | −3.23 | |
| Parahippocampal Gyrus | rostral BA 35/36 (R) | 110 | −3.54 |
| BA 28/34 (entorhinal cortex) (L) | 115 | −3.35 | |
| BA 28/34 (entorhinal cortex) (R) | 116 | −3.45 | |
| temporal agranular insular cortex (R) | 118 | −2.52 | |
| Basal Ganglia | ventromedial putamen (R) | 226 | −2.85 |
| Lower FSD in deletion carriers experiencing positive psychotic symptoms | |||
| Region’s Location | Region's name (hemisphere) | Region's ID | Brain salience |
| Superior Frontal Gyrus | medial BA 6 (L) | 9 | 2.53 |
| medial BA 6 (R) | 10 | 2.32 | |
| Paracentral Lobule | BA1/2/3 (lower limb region) (R) | 66 | 2.67 |
| BA 4 (L) | 67 | 2.49 | |
| Parahippocampal Gyrus | posterior parahippocampal gyrus (L) | 113 | 3.34 |
| posterior parahippocampal gyrus (R) | 114 | 2.35 | |
| area TH (medial PPHC) (R) | 120 | 2.63 | |
| Inferior Parietal Lobule | caudal BA 40 (R) | 142 | 2.78 |
| Precuneus | medial BA 7 (L) | 147 | 2.50 |
| Cingulate Gyrus | rostroventral BA 24 (L) | 177 | 4.04 |
| rostroventral BA 24 (R) | 178 | 3.38 | |
| pregenual BA 32 (L) | 179 | 3.14 | |
| caudal BA 23 (L) | 185 | 2.89 | |
| caudal BA 23 (R) | 186 | 4.89 | |
| Thalamus | sensory thalamus (R) | 234 | 3.70 |