TABLE 10.
Mean plasma concentration-time data of TMP, FA, NK, and ISP in the powder and pill groups (n = 3,−x ± SE).
| Times (min) | Powder group (ng/ml) | Pill group (ng/ml) | ||||||
|---|---|---|---|---|---|---|---|---|
| Tetramethylpyrazine | Ferulic acid | Nodakenin | Isoimperatorin | Tetramethylpyrazine | Ferulic acid | Nodakenin | Isoimperatorin | |
| 5 | 0.75 ± 0.42 | 259.07 ± 120.79 | 22.07 ± 4.82 | 1.23 ± 0.23 | 1.47 ± 0.72 | 343.17 ± 140.30 | 29.40 ± 10.36 | 0.47 ± 0.37 |
| 15 | 0.40 ± 0.18 | 247.30 ± 121.94 | 18.47 ± 4.94 | 0.75 ± 0.29 | 2.00 ± 0.34 | 314.60 ± 106.36 | 31.97 ± 13.34 | 0.67 ± 0.23 |
| 30 | 0.50 ± 0.24 | 286.73 ± 138.47 | 21.13 ± 2.60 | 1.13 ± 0.60 | 0.63 ± 0.13 | 365.77 ± 116.84 | 50.07 ± 10.52 | 2.10 ± 1.28 |
| 45 | 0.75 ± 0.28 | 284.63 ± 90.45 | 13.27 ± 2.39 | 0.55 ± 0.37 | 0.83 ± 0.37 | 449.57 ± 249.11 | 36.47 ± 14.17 | 0.50 ± 0.08 |
| 60 | 0.60 ± 0.41 | 243.73 ± 131.13 | 14.8 ± 5.01 | 0.30 ± 0.10 | 0.80 ± 0.57 | 533.23 ± 321.95 | 34.60 ± 6.04 | 1.10 ± 0.30 |
| 90 | 0.45 ± 0.29 | 213.93 ± 84.55 | 17.30 ± 4.33 | 1.93 ± 1.34 | 0.40 ± 0.25 | 512.13 ± 364.76 | 18.90 ± 9.49 | 1.10 ± 0.41 |
| 120 | 0.63 ± 0.26 | 127.60 ± 26.37 | 7.57 ± 2.43 | 1.27 ± 0.73 | 0.87 ± 0.43 | 654.70 ± 387.64 | 29.87 ± 2.61 | 0.30 ± 0.08 |
| 150 | 1.23 ± 1.08 | 145.07 ± 5.88 | 8.73 ± 1.70 | 1.03 ± 0.27 | 0.80 ± 0.35 | 457.73 ± 212.31 | 26.33 ± 3.68 | 0.23 ± 0.09 |
| 180 | 1.07 ± 0.35 | 250.23 ± 65.40 | 11.53 ± 3.63 | 0.70 ± 0.40 | 0.57 ± 0.15 | 564.33 ± 359.83 | 40.03 ± 4.18 | 0.60 ± 0.16 |
| 240 | 0.50 ± 0.10 | 176.87 ± 48.15 | 16.60 ± 6.68 | 0.50 ± 0.08 | 0.83 ± 0.25 | 623.13 ± 525.94 | 38.73 ± 9.29 | 1.13 ± 0.79 |
| 360 | 0.80 ± 0.56 | 188.07 ± 64.80 | 13.00 ± 5.33 | 0.40 ± 0.08 | 0.15 ± 0.04 | 576.70 ± 508.83 | 30.43 ± 7.08 | 0.17 ± 0.03 |
| 480 | 0.93 ± 0.58 | 151.50 ± 20.45 | 19.83 ± 5.26 | 0.60 ± 0.24 | 1.13 ± 0.55 | 213.17 ± 86.83 | 33.40 ± 13.54 | 0.03 ± 0.15 |
| 720 | 0.53 ± 0.19 | 120.20 ± 28.10 | 11.27 ± 0.88 | 0.15 ± 0.04 | 1.23 ± 0.71 | 233.73 ± 66.95 | 18.93 ± 8.32 | 0.27 ± 0.09 |
| 1440 | 0.43 ± 0.20 | 96.03 ± 46.30 | 2.97 ± 0.27 | 0.10 ± 0.00 | 0.70 ± 0.46 | 116.27 ± 18.57 | 12.40 ± 7.75 | 0.50 ± 0.40 |