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. 2022 Jun 9;13:893552. doi: 10.3389/fphar.2022.893552

TABLE 10.

Mean plasma concentration-time data of TMP, FA, NK, and ISP in the powder and pill groups (n = 3,−x ± SE).

Times (min) Powder group (ng/ml) Pill group (ng/ml)
Tetramethylpyrazine Ferulic acid Nodakenin Isoimperatorin Tetramethylpyrazine Ferulic acid Nodakenin Isoimperatorin
5 0.75 ± 0.42 259.07 ± 120.79 22.07 ± 4.82 1.23 ± 0.23 1.47 ± 0.72 343.17 ± 140.30 29.40 ± 10.36 0.47 ± 0.37
15 0.40 ± 0.18 247.30 ± 121.94 18.47 ± 4.94 0.75 ± 0.29 2.00 ± 0.34 314.60 ± 106.36 31.97 ± 13.34 0.67 ± 0.23
30 0.50 ± 0.24 286.73 ± 138.47 21.13 ± 2.60 1.13 ± 0.60 0.63 ± 0.13 365.77 ± 116.84 50.07 ± 10.52 2.10 ± 1.28
45 0.75 ± 0.28 284.63 ± 90.45 13.27 ± 2.39 0.55 ± 0.37 0.83 ± 0.37 449.57 ± 249.11 36.47 ± 14.17 0.50 ± 0.08
60 0.60 ± 0.41 243.73 ± 131.13 14.8 ± 5.01 0.30 ± 0.10 0.80 ± 0.57 533.23 ± 321.95 34.60 ± 6.04 1.10 ± 0.30
90 0.45 ± 0.29 213.93 ± 84.55 17.30 ± 4.33 1.93 ± 1.34 0.40 ± 0.25 512.13 ± 364.76 18.90 ± 9.49 1.10 ± 0.41
120 0.63 ± 0.26 127.60 ± 26.37 7.57 ± 2.43 1.27 ± 0.73 0.87 ± 0.43 654.70 ± 387.64 29.87 ± 2.61 0.30 ± 0.08
150 1.23 ± 1.08 145.07 ± 5.88 8.73 ± 1.70 1.03 ± 0.27 0.80 ± 0.35 457.73 ± 212.31 26.33 ± 3.68 0.23 ± 0.09
180 1.07 ± 0.35 250.23 ± 65.40 11.53 ± 3.63 0.70 ± 0.40 0.57 ± 0.15 564.33 ± 359.83 40.03 ± 4.18 0.60 ± 0.16
240 0.50 ± 0.10 176.87 ± 48.15 16.60 ± 6.68 0.50 ± 0.08 0.83 ± 0.25 623.13 ± 525.94 38.73 ± 9.29 1.13 ± 0.79
360 0.80 ± 0.56 188.07 ± 64.80 13.00 ± 5.33 0.40 ± 0.08 0.15 ± 0.04 576.70 ± 508.83 30.43 ± 7.08 0.17 ± 0.03
480 0.93 ± 0.58 151.50 ± 20.45 19.83 ± 5.26 0.60 ± 0.24 1.13 ± 0.55 213.17 ± 86.83 33.40 ± 13.54 0.03 ± 0.15
720 0.53 ± 0.19 120.20 ± 28.10 11.27 ± 0.88 0.15 ± 0.04 1.23 ± 0.71 233.73 ± 66.95 18.93 ± 8.32 0.27 ± 0.09
1440 0.43 ± 0.20 96.03 ± 46.30 2.97 ± 0.27 0.10 ± 0.00 0.70 ± 0.46 116.27 ± 18.57 12.40 ± 7.75 0.50 ± 0.40