Table 1.
Demographic and clinicopathologic characteristics of the surgery and RFA groups
Characteristics | Surgery group (n = 150) | RFA group (n = 151) | p value |
---|---|---|---|
Patient factors | |||
Age, median (IQR), years | 68 (63–74) | 69 (63–74) | 0.85 |
Sex, male:female | 112:38 | 108:43 | 0.54 |
Performance status, n (%) | |||
0 | 147 (98) | 146 (97) | |
1 | 3 (2) | 4 (3) | 0.56 |
2 | 0 | 1 (1) | |
Child-Pugh score, n (%) | |||
5 | 117 (78) | 129 (85) | |
6 | 22 (15) | 20 (13) | 0.07 |
7 | 10 (7) | 2 (1) | |
Hepatitis C virus infection, n (%) | 97 (65) | 94 (62) | 0.66 |
Hepatitis B virus infection,* n (%) | 27 (18) | 33 (22) | 0.42 |
Use of antiviral therapy, n (%) | 23 (15) | 21 (14) | 0.58 |
Serum albumin level, median (IQR), g/dL | 4.0 (3.7–4.3) | 4.1 (3.7–4.4) | 0.48 |
Total bilirubin level, median (IQR), mg/dL | 0.7 (0.5–1.0) | 0.8 (0.6–1.0) | 0.58 |
Prothrombin time, median (IQR), % | 91 (81–99) | 94 (86–100) | 0.01 |
Platelet count, median (IQR), 104/µL | 13.0 (9.9–16.8) | 13.5 (9.8–17.5) | 0.62 |
Creatinine level, median (IQR), mg/dL | 0.7 (0.6–0.9) | 0.7 (0.6–0.9) | 0.73 |
Absence of ascites,* †n (%) | 145 (97) | 149 (99) | 0.16 |
History of other cancers,* n (%) | 13 (9) | 7 (5) | 0.23 |
Comorbidity, ischemic heart disease, n (%) | 2 (1) | 2 (1) | 0.61 |
Pretreatment TACE* | 11 (7) | 12 (8) | 0.59 |
HCC clinical factors | |||
HCCs, n | 1 (1–1) | 1 (1–1) | 0.97 |
≥2, n (%) | 15 (10) | 15 (10) | 0.98 |
Largest HCC diameter, median (IQR), cm | 1.8 (1.5–2.2) | 1.8 (1.5–2.3) | 0.89 |
≤2.0 cm, n (%) | 98 (65) | 101 (67) | 0.78 |
HCC histopathologic factors, n (%) | |||
HCC | 131 (87) | 30 (20) | − |
Well-differentiated | 39 (26) | 10 (7) | |
Moderately differentiated | 85 (57) | 16 (11) | |
Poorly differentiated | 7 (5) | 4 (3) | |
Unknown | 19 (13) | 121 (80) |
* Data missing on hepatitis B virus infection for 1 patient, the absence of ascites for 1 patient, history of other cancers for 1 patient, comorbidity of ischemic heart disease for 1 patient, and pretreatment TACE for 1 patient. †Including patients treated with diuretics.