Fig. 2.

Visual acuity in patients with uveal melanoma treated with PT, with or without a subsequent adjuvant intervention. Bars show values recorded directly after PT (dark blue), 3 months after PT (medium blue), and 12 months after PT (light blue), grouped by the adjuvant treatment type. A mixed generalized linear model showed a significant interaction between the treatment type and time (p = 0.018). *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, and ****p ≤ 0.0001 indicate significant changes between assessments, detected with the paired Wilcoxon signed-rank test. ns, not significant; PT, proton therapy.