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. 2022 Jun 9;13:914828. doi: 10.3389/fmicb.2022.914828

Table 1.

The effect of different fermentation medium compounds on the production of yellow Monascus pigments in submerged fermentation for 10 days at 30°C and agitated at 150 rpm in the dark.

Composition Compound Concentration (g/L) inMPs (U/ml) exMPs (U/ml) T-MPs (U/ml) exMPs/T-MPs (%) Increased by (%)
CK 10.67 22.68 33.35 68.01
Growth factor B1 0.2 17.79 29.82 47.61 62.63 42.76
B3 0.2 15.06 27.86 42.52 65.52 27.50
B5 0.2 15.10 36.53 51.63 70.75 54.81
B6 0.2 12.04 28.22 40.26 70.09 20.72
VC 0.2 14.57 32.28 46.85 68.90 40.48
B5 0.1 10.76 24.84 35.60 69.78 6.75
0.2 15.10 36.53 51.63 70.75 54.81
0.3 15.28 40.17 55.45 72.45 66.27
0.4 19.09 44.49 63.58 69.98 90.64
0.5 15.38 33.24 48.62 68.37 45.79
Nitrogen source Peptone 5 23.66 36.70 60.36 60.80 80.99
10 26.80 46.50 73.30 63.44 119.79
15 36.76 52.80 89.56 58.95 168.55
20 21.48 46.35 67.83 68.33 103.39
Malt extract 5 27.64 54.65 82.29 66.41 146.75
10 35.80 59.35 95.15 62.37 185.31
15 26.46 48.45 74.91 64.68 124.62
20 23.84 44.55 68.39 65.14 105.07
NaNO3 1 14.45 28.20 42.65 51.24 27.89
3 19.90 45.65 65.55 69.64 96.55
5 28.40 51.50 79.90 64.46 139.58
7 18.59 39.46 58.05 67.96 74.06
9 11.85 32.80 44.65 73.46 33.88
Metal
ion
Mg2+ 0.05 15.62 29.30 44.92 65.23 34.69
0.1 15.58 36.73 52.31 70.22 56.85
0.2 17.65 43.27 60.92 71.03 82.67
0.5 19.59 36.81 56.40 65.26 69.12
Mn2+ 0.01 13.65 39.12 52.77 74.13 58.23
0.05 15.17 48.16 63.33 76.05 89.90
0.1 19.63 54.88 74.51 73.65 123.42
0.2 17.46 34.08 51.54 66.12 54.54
Fe2+ 0.5 12.35 29.57 41.92 70.55 25.70
1 13.20 34.15 47.35 72.13 41.98
1.5 13.08 39.76 52.84 75.25 58.44
2 16.32 28.04 44.36 63.22 33.01
Ca2+ 0.5 9.73 24.23 33.96 71.35 1.83
1 13.01 30.91 43.92 70.38 31.69
1.5 17.16 36.92 54.08 68.26 62.16
2 11.60 25.30 36.90 68.56 10.64
Zn2+ 0.05 17.99 47.03 65.02 72.33 94.96
0.1 22.41 52.65 75.06 70.15 125.07
0.2 26.75 57.83 84.58 68.37 153.61
0.5 18.78 42.22 61.00 69.22 82.91

The data were expressed as the mean from three experiments.