TABLE 1.
Antimicrobial activities of NCR peptides against A. baumannii and C. albicans.
| Name | Amino acid sequence | pI | NC | MBC | MFC |
|---|---|---|---|---|---|
| CaNCR13 | KPCQSDKDCKKFACRKPKVPKCINGFCKCVRIW-COOH | 9.93 | 7.60 | 6.25 | 6.25 |
| CaNCR63 | KMICKTRVDCKKYRCPRSKIKDCVKGYCRCVRKK-COOH | 10.48 | 11.60 | 6.25 | 3.125 |
| CaNCR631-20 | KMICKTRVDCKKYRCPRSKI-CONH2 | 10.85 | 7.80 | 6.25 | 25 |
| CaNCR6315-34 | CPRSKIKDCVKGYCRCVRKK-CONH2 | 10.65 | 7.70 | 6.25 | 3.125 |
| MsNCR443 | ESIECRTVADCPKLISSKFVIKCIKKRCVAQFFK-COOH | 9.68 | 4.70 | 6.25 | 6.25 |
| MsNCR46316-35 | CKPKRGVNFRCRKGKCFPVR-CONH2 | 11.79 | 8.80 | 1.6 | 3.125 |
| MsNCR46317-30 | KPKRGVNFRCRKGK-CONH2 | 12.45 | 7.90 | 3.125 | 3.125 |
| PsNCR349 | YNLKYCTNDKDCPTMMCFPPDVSKCVWKTCYCVQKHKKKLKKKKKLTFNM-COOH | 9.93 | 9.70 | 3.125 | 3.125 |
| PsNCR34926-50 | VWKTCYCVQKHKKKLKKKKKLTFNM-CONH2 | 11.06 | 11.00 | 3.125 | 3.125 |
| PsNCR34931-50 | YCVQKHKKKLKKKKKLTFNM-CONH2 | 11.24 | 10.00 | 6.25 | 1.6 |
| PsNCR352 | PSGLRCLNDSDCLRFRCSKIYKVLCIERRCRRIKMH-COOH | 10.30 | 6.80 | 6.25 | 3.125 |
| Ampicillin | 10240 | ||||
| Miconazole | 50580 |
pI, isoelectric point; NC, net charge; MBC, minimal bactericidal concentrations of the peptides and ampicillin against A. baumannii in μM; MFC, minimal fungicidal concentrations of the peptides and miconazole against C. albicans in μM.