Table 4.

Risk of cardiometabolic disease by baseline AST and ALT.

Disease status	Baseline AST (IU/L)		Baseline ALT (IU/L)
	HR (95% CI)	P	HR (95% CI)	P
Diabetes mellitus
Model 1	1.018 (1.005–1.030)	0.005	1.016 (1.008–1.024)	<0.001
Model 2	1.018 (1.005–1.030)	0.005	1.016 (1.009–1.025)	<0.001
Model 3	1.017 (1.004–1.029)	0.008	1.015 (1.007–1.023)	<0.001
Model 4	1.019 (1.006–1.032)	0.003	1.016 (1.008–1.025)	<0.001
Metabolic syndrome
Model 1	0.980 (0.965–0.996)	0.012	0.992 (0.988–0.997)	0.001
Model 2	0.980 (0.965–0.996)	0.014	0.992 (0.987–0.996)	<0.001
Model 3	0.982 (0.966–0.998)	0.026	0.995 (0.991–0.999)	0.029
Model 4	0.987 (0.971–1.003)	0.116	0.996 (0.992–1.000)	0.075

HR, hazard ratio; CI, confidence interval.

Model 1 is unadjusted.

Model 2: adjusted for age, sex and income.

Model 3: adjusted for model 2, waist circumference, SBP and DBP.

Model 4: adjusted for model 3, HbA1c, triglyceride, cholesterol, HDL and eGFR.

p <0.05 used and statistically significant results bolded.