Table 2.

Brain activity affected by emotion regulation, depression, and amygdala-PFC tract lesions

Effect/region	x	y	z	Cluster Size	t	pFWE	Β
Emotion regulation
Amygdala	18	−3	−15	54	−3.00	0.033	*
Middle frontal gyrus	−33	54	−3	27	4.03	0.049	*
Depression
Amygdala	−18	−6	−15	54	3.03	0.024	0.39
Depression × Strategic LL
Amygdala	−18	−9	−15	189	3.53	0.010	0.48
Amygdala	24	−3	−21	108	3.41	0.012	0.51
Amygdala	−30	−6	−24	189	3.21	0.021	0.49

x, y, and z correspond to coordinates of voxels in the MNI space with peak effect size in a cluster of significant voxels. The cluster size corresponds to the volume of significant voxels according to α_FWE = 0.05 in mm³. *Please note that the regression coefficient for the intercept (i.e. the constant regressor of interest in the analysis of main effects of emotion regulation) cannot be standardized due to the lack of variation in this variable. Consequently, we cannot report the standardized regression coefficient as effect size measure for this proof-of-principle analysis.