Table 2.

Functional population distributions of characterized primary afferent populations from naïve (A) and SCI (B) mice 24 hr following injury. Both groups of mice show similar distributions of A- and C-fibers as well as resting membrane potentials (RMP). However, analysis did reveal an increase in the percentage of CC neurons characterized from SCI mice, *=statistical significance relative to naïve mice, Fisher’s exact test, t-test, p <.05.

Phenotype	Fiber Type	Function	% Naïve (N = 67)	%SCI (N = 81)	Naïve RMP (mV)	SCI RMP (mV)
A-LTMR	A	Low threshold mechanoreceptor	16.4	12.4	−46.61 ± 3.63	−56.13 ± 4.20
A-HTMR	A	High threshold mechanoreceptor	13.4	16.1	−53.45 ± 4.28	−60.12 ± 3.69
CM	C	Mechanoreceptor	9.0	7.4	−42.13 ± 6.36	−50.30 ± 3.41
CC	C	Cold sensitive	0.0	3.7	–	−39.43 ± 5.43
CH	C	Heat sensitive	11.9	12.4	−39.65 ± 4.25	−44.69 ± 4.69
CMC	C	Mechanical + cold sensitive	3.0	3.7	−42.25 ± 0.67	−58.50 ± 5.93
CMH	C	Mechanical + heat sensitive	37.3	33.3	−46.13 ± 1.93	−44.23 ± 2.02
CMHC	C	Mechanical + heat + cold sensitive	9.0	11.1	−53.07 ± 3.56	−49.40 ± 2.47