(a) Schematic illustration of the fabrication of PDA, melanin, Cu(II) loaded PDA, and Cu(II) loaded melanin nanoparticles for antibacterial activity. (b) SEM and TEM images of melanin, PDA, Cu(II) loaded melanin, and Cu(II) loaded PDA nanoparticles. (c) The E. coli and S. aureus inhibition efficiency of ampicillin, PDA, Cu(II) loaded PDA NPs, melanin, Cu(II) loaded melanin NPs and CuCl2, and (d) the corresponding live/dead fluorescent images. (e) Wound healing assessment for S. aureus infected wound, with PDA, Cu(II) loaded PDA nanoparticles within 14 days. With permission, reprinted from Ref. [114]. Copyright 2021 The Royal Society of Chemistry.