TABLE 1.
Uncharacterized thrombospondin-related proteins in Toxoplasma gondii.
| ToxoDB gene ID | Chr. n. | ToxoDB annotation | FCSa | #TSP1 domains | Other domains | LP | TMR | Length | Proteomicsb | Transcriptomicsc |
| TGME49_223480 | X | Sushi domain-containing protein | −3.9 | 16 | Sushi, NL | No | Yes | 4752 | nd | EES |
| TGME49_247195 | XII | Microneme protein MIC15 | −3.31 | 3 | H-type lectin | Yes | Yes | 2909 | T,S,B | T,S,B |
| TGME49_277910 | XII | TSP1 domain-containing protein | −2.95 | 1 | – | No | Yes | 1232 | T | All stages |
| TGME49_279420 | IX | Hypothetical protein | −1.96 | 1 | – | No | No | 1329 | T,S,B | T,S,B |
| TGME49_209060 | Ib | TSP1 domain-containing protein | −1.7 | 7 | – | Yes | Yes | 876 | T,S,B | All stages |
| TGME49_247970 | XII | Hypothetical protein | −0.96 | 2 | – | Yes | Yes | 1237 | nd | EES |
| TGME49_319992 | IV | Hypothetical protein | −0.48 | 1 | – | No | No | 223 | nd | EES |
| TGME49_218310 | XII | Microneme protein MIC14 | 0.28 | 3 | – | No | Yes | 968 | nd | All stages |
| TGME49_237585 | X | Hypothetical protein | 1.41 | 2 | – | No | Yes | 1253 | T* | EES |
aFCS: fitness conferring score (Sidik et al., 2016) indicating protein essentiality (highly negative values) or dispensability (positive values).
bStages in which the protein was identified by mass-spectrometry according to proteomic studies reported in ToxoDB.
cStages with the relative highest abundance of gene transcript as deduced from ToxoDB data.
*Weak single-peptide identification.
B, bradyzoite; EES, enteroepithelial stages; LP, leader peptide; nd, no data; NL, Notch domain; S, sporozoite; T, tachyzoite; TMR, transmembrane region; vWA, von Willebrand factor type A domain.