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. 2022 Jun 22;7(8):817–824. doi: 10.1001/jamacardio.2022.1651

Table 3. Adverse Events.

Events No. (%)
Usual-care CR (n = 80) Early CR (n = 78)
Serious adverse events
Total 14 (17.5) 18 (23.1)
Death 2 (2.5) 1 (1.3)
Sternal instability 1 (1.3) 4 (5.1)
Sternal wound infection 1 (1.3) 0 (0)
Musculoskeletal pain 1 (1.3) 2 (2.6)
Transient ischemic attack 1 (1.3) 2 (2.6)
LRTI 3 (3.8) 2 (2.6)
Fluid overload 2 (2.5) 0 (0)
Anemia 1 (1.3) 1 (1.3)
Atrial fibrillation 2 (2.5) 1 (1.3)
Endocarditis 0 (0) 1 (1.3)
Acute kidney injury 0 (0) 1 (1.3)
Pulmonary embolism 0 (0) 1 (1.3)
Road traffic accident 0 (0) 1 (1.3)
Eye casualty 0 (0) 1 (1.3)
Adverse events
Total 46 (57.5) 58 (74.4)
Arrythmia 14 (17.5) 10 (12.8)
Superficial wound infection 8 (10.0) 10 (12.8)
LRTI 4 (5.0) 9 (11.5)
Pleural effusion 5 (6.3) 0 (0)
Excessive dyspnea 1 (1.3) 8 10.3)
Presyncope 2 (2.5) 2 (2.6)
Musculoskeletal pain 3 (3.8) 5 (6.4)
Fluid retention 1 (1.3) 2 (2.6)
Vertigo 0 (0) 1 (1.3)
Urinary tract infection 2 (2.5) 1 (1.3)
Hypertension >180/100 mm Hg 1 (1.3) 1 (1.3)
Hematuria 1 (1.3) 3 (3.8)
Leg wound bleed 0 (0) 1 (1.3)
Constipation 0 (0) 1 (1.3)
Osteoarthritis 0 (0) 1 (1.3)
Perirectal bleed 0 (0) 1 (1.3)
Deep venous thrombosis 1 (1.3) 0 (0)
Panic attack 1 (1.3) 0 (0)
Diarrhea 0 (0) 1 (1.3)
Cellulitis 0 (0) 1 (1.3)
Epilepsy 1 (1.3) 0 (0)

Abbreviations: CR, cardiac rehabilitation; LRTI, lower respiratory tract infection.