Table 1. Model-Based Estimates of Percentage Excess Weight Loss (EWL), Body Mass Index (BMI), Percentage Excess BMI Loss, and Percentage Total Weight Loss^a.

Time	LSG	LRYGB	LRYGB vs LSG difference (95% CI)	P value
%EWL, No.b,c,d
Baseline	121	119	NA	NA
0.5 y	119	111	4.7 (−0.4 to 9.7)	NA
1 y	111	108	5.7 (0.6 to 10.8)	NA
3 y	108	100	8.6 (3.4 to 13.7)	NA
5 y	98	95	8.4 (3.1 to 13.7)	NA
7 y	91	91	9.0 (3.6 to 14.3)	NA
10 y	98	95	8.4 (3.1 to 13.6)	NA
BMI, mean estimate (95% CI)c,e,f
Baseline	47.3 (46.2 to 48.4)	48.4 (47.2 to 49.5)
0.5 y	35.8 (34.7 to 37.0)	35.3 (34.1 to 36.5)	−0.5 (−2.1 to 1.1)	.54
1 y	34.4 (33.3 to 35.6)	33.6 (32.4 to 34.8)	−0.9 (−2.5 to 0.8)	.30
3 y	35.3 (34.2 to 36.5)	34.0 (32.8 to 35.2)	−1.3 (−2.9 to 0.3)	.12
5 y	36.5 (35.4 to 37.7)	35.4 (34.2 to 36.6)	−1.1 (−2.8 to 0.6)	.19
7 y	37.1 (36.0 to 38.3)	35.8 (34.6 to 37.0)	−1.3 (−3.0 to 0.4)	.13
10 y	37.8 (36.6 to 39.0)	36.5 (35.3 to 37.7)	−1.3 (−3.0 to 0.4)	.13
%EBL, mean estimate (95% CI)c,e,g	50.8 (48.0 to 53.7)	58.2 (55.3 to 61.2)	7.4 (3.4 to 11.5)	<.001
%TWL, mean estimate (95% CI)c,e,h	23.4 (22.1 to 24.7)	26.9 (25.6 to 28.2)	3.5 (1.6 to 5.4)	<.001

Abbreviations: BMI, body mass index; %EBL, percentage excess BMI loss; %EWL, percentage excess weight loss; LSG, laparoscopic sleeve gastrectomy; LRYGB, laparoscopic Roux-en-Y gastric bypass; NA, not applicable; %TWL, percentage total weight loss.

^a All results adjusted for center and diabetes status.

^b Equivalence design was used in the analyses, and equivalence margins were set from −9 to 9.

^c Repeated-measurements analysis of variance.

^d Percentage EWL calculated as (initial weight − follow-up weight) / (initial weight − ideal weight for BMI 25).

^e Superiority design was used in the analysis.

^f P < .001 for operation × time interaction.

^g P = .36 for operation × time interaction; P < .001 for main effect of operation; P < .001 for main effect of time.

^h P = .49 for operation × time interaction; P < .001 for main effect of operation and P < .001 for main effect of time.