Table 2. Proton Pump Inhibitor (PPI) Intake, Gastroesophageal Reflux Disease (GERD) Symptoms, GERD–Health-Related Quality of Life (HRQL), and Endoscopic Findings Between Laparoscopic Sleeve Gastrectomy (LSG) vs Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) at 10 Years.
| No./total No. (%) | P value | ||
|---|---|---|---|
| LSG (n = 91) | LRYGB (n = 85) | ||
| All patients who underwent endoscopy | 91/121 (75.2) | 85/119 (71.4) | |
| PPI intake preoperatively | 11/89 (12) | 5/81 (6) | .20a |
| PPI intake at 10 y | 58/90 (64) | 30/84 (36) | <.001a |
| GERD symptoms | |||
| No symptoms preoperatively or at any point | 18/90 (20) | 39/85 (46) | <.001a |
| Symptoms similar to preoperatively | 16/90 (18) | 6/85 (7) | |
| Symptoms alleviated postoperatively | 12/90 (13) | 32/85 (38) | |
| Symptoms worsened postoperatively | 44/90 (49) | 8/85 (9) | |
| GERD-HRQL total score, median (range) | 10.5 (0.0-47.0) | 0.0 (0.0-47.0) | <.001b |
| Hiatal herniac | 57/91 (63) | NA | NA |
| All patients with esophagitis | 28/91 (31) | 6/85 (7) | <.001d |
| Los Angeles classification | |||
| Gradus A | 14/28 (50) | 3/6 (50) | .66a |
| Gradus B | 12/28 (43) | 2/6 (33) | |
| Gradus C | 2/28 (7) | 1/6 (17) | |
| Gradus D | 0/28 (0) | 0/6 (0) | |
| PPI intake preoperatively | 3/28 (11) | 1/5 (20) | .50a |
| PPI intake at 10 y | 16/28 (57) | 2/5 (40) | .64a |
| GERD symptoms | |||
| No symptoms preoperatively or at any point | 6/28 (21) | 3/6 (50) | .02a |
| Symptoms similar to preoperatively | 6/28 (21) | 0/6 (0) | |
| Symptoms alleviated postoperatively | 4/28 (14) | 3/6 (50) | |
| Symptoms worsened postoperatively | 12/28 (43) | 0/0 (0) | |
| GERD-HRQL total score, median (range) | 15.0 (0.0-47.0) | 0.0 (0.0-18.0) | .03b |
| Hiatal herniac | 26/28 (93) | NA | NA |
| All patients with Barrett esophaguse | 4/91 (4) | 3/85 (4) | .29a |
| PPI intake preoperatively | 0/4 (0) | 1/2 (50)f | .33a |
| PPI intake at 10 y | 3/4 (75) | 2/3 (67) | .99a |
| GERD symptoms | |||
| No symptoms preoperatively or at any point | 0/4 (0) | 1/3 (33) | .49a |
| Symptoms similar to preoperatively | 1/4 (25) | 0/3 (0) | |
| Symptoms alleviated postoperatively | 0/4 (0) | 1/3 (33) | |
| Symptoms worsened postoperatively | 3/4 (75) | 1/3 (33) | |
| GERD-HRQL total score, median (range) | 11.0 (3.0-20.0) | 4.5 (0.0-9.0) | .25b |
| Hiatal herniac | 2/4 (50) | NA | NA |
Abbreviation: NA, not applicable.
a
Fisher exact test.
b
Nonparametric Mann-Whitney U test.
c
Descriptive data; hiatal hernias in LRYGB group could not be evaluated reliably owing to problems with inverse.
d
χ2 Test.
e
All short-segment de novo Barrett esophagus.
f
One patient had missing information.