TABLE 1.
Inhibitory effects of 13 compounds on GluN1/GluN3A receptors.
| Compound | I drug/I control | n | Compound | I drug/I control | n |
|---|---|---|---|---|---|
| DMSO | 0.94 ± 0.01 | 3 | Rhein | 0.80 ± 0.04 | 4 |
| Avasimibe | 0.86 ± 0.03 | 3 | S0859 | 0.48 ± 0.02 | 6 |
| GSK2334470 | 0.84 ± 0.04 | 6 | TAK285 | 0.92 ± 0.06 | 3 |
| IC261 | 0.88 ± 0.01 | 3 | Tirapazamine | 1.03 ± 0.05 | 3 |
| KN93 Phosphate | 0.90 ± 0.02 | 6 | WAY200070 | 0.53 ± 0.02 | 3 |
| Lonafarnib | 0.98 ± 0.02 | 3 | WZB117 | 0.08 ± 0.02 | 9 |
| NH125 | 0.84 ± 0.03 | 3 | SU6668 | 0.89 ± 0.04 | 3 |
Data are shown as the mean ± SEM. All recordings were performed on GluN1/GluN3A Flp-in T-REx 293 stable cell lines. The order of drug application was the same as in FDSS/μCell Ca2+ imaging, and the representative current traces are given in Supplementary Figure S4.