HOP-62 human lung cancer cell line activity of QRT and QRT–AuQDsa.
Drug concentrations (μmolar) calculated from graph | |||
---|---|---|---|
HOP-62 | LC50 | TGI | GI50* |
QRT | >100 | 50.43 | <0.1 |
QRT–AuQDs | >100 | 40.47 | <0.1 |
ADR | <0.1 | 15.2 | <0.1 |
LC50 = concentration of drug causing 50% cell death, GI50 = concentration of drug causing 50% inhibition of cell growth, TG = concentration of drug causing total inhibition of cell growth, ADR = adriamycin, the positive control compound, a GI50 value of ≤10−6 molar (i.e. 1 μmolar) is considered to demonstrate activity.50–52