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. 2022 Jun 23;12(29):18425–18430. doi: 10.1039/d2ra02529a

HOP-62 human lung cancer cell line activity of QRT and QRT–AuQDsa.

Drug concentrations (μmolar) calculated from graph
HOP-62 LC50 TGI GI50*
QRT >100 50.43 <0.1
QRT–AuQDs >100 40.47 <0.1
ADR <0.1 15.2 <0.1
a

LC50 = concentration of drug causing 50% cell death, GI50 = concentration of drug causing 50% inhibition of cell growth, TG = concentration of drug causing total inhibition of cell growth, ADR = adriamycin, the positive control compound, a GI50 value of ≤10−6 molar (i.e. 1 μmolar) is considered to demonstrate activity.50–52