Antimicrobial activity of the 2-aryloxy-1,4-naphthoquinone derivativs, expressed as minimal inhibitory concentration (μmol L−1).
| Compound | Molar mass (g mol−1) | MIC (μmol L−1) | ||
|---|---|---|---|---|
| S. aureus | E. coli | C. albicans | ||
| 34 | 280.275 | 3568 | 892 | 3568 |
| 35 | 280.275 | 223 | 3568 | 446 |
| 36 | 280.275 | 1784 | 3568 | 3568 |
| 37 | 295.246 | 21.2 | 3387 | 3387 |
| 38 | 329.145 | 760 | 3038 | 190 |
| 39 | 329.145 | 3038 | 3038 | 3038 |
| 40 | 408.041 | 2450 | 2450 | 2450 |
| 41 | 486.937 | 2054 | 2054 | 2054 |
| 42 | 319.139 | 3133 | 3133 | 3133 |
| 43 | 492.563 | 2030 | 2030 | 2030 |
| 44 | 326.345 | 3064 | 3064 | 3064 |
| 45 | 306.355 | 3264 | 3264 | 3264 |
| 46 | 284.694 | 220 | 3512 | 220 |
| 47 | 284.694 | 878 | 3512 | 220 |
| 48 | 284.694 | 439 | 3512 | 439 |
| 49 | 250.249 | 250 | 250 | 4000 |
| 50 | 295.246 | 13 | 1693 | 85 |
| 51 | 353.584 | 2828 | 2828 | 2828 |
| 52 | 353.584 | 2828 | 2828 | 2828 |
| 53 | 312.747 | 3197 | 3197 | 3197 |
| 54 | 306.355 | 3262 | 3262 | 3262 |
| 55 | 445.679 | 0.34 | 0.56 | 2244 |
| 56 | 320.339 | 1561 | 3122 | 3122 |
| 57 | 540.562 | 925 | 1850 | 1850 |
| 58 | 580.626 | 431 | 1722 | 1722 |
| 60 | 264.276 | 473 | 3784 | 237 |
| 61 | 264.276 | 237 | 3784 | 473 |
| 62 | 295.246 | 212 | 3387 | 3387 |
| 63 | 319.139 | 49 | 3133 | 3133 |
| Gentamicin sulphate | 1488.8 | 0.52 | 0.52 | — |
| Ketoconazole | 541.43 | — | — | 0.56 |