Assessment of the effect of substituents in the phenolic moiety on the relative antimicrobial action of the synthesized compounds.
Compound | Molar mass (g mol−1) | MIC49/MICcompound | ||
---|---|---|---|---|
S. aureus | E. coli | C. albicans | ||
34 | 280.275 | 0.07 | 0.28 | 1.12 |
35 | 280.275 | 1.12 | 0.07 | 8.97 |
36 | 280.275 | 0.14 | 0.07 | 1.12 |
37 | 295.246 | 11.79 | 0.07 | 1.18 |
38 | 329.145 | 0.33 | 0.08 | 21.05 |
39 | 329.145 | 0.08 | 0.08 | 1.32 |
40 | 408.041 | 0.10 | 0.10 | 1.63 |
41 | 486.937 | 0.12 | 0.12 | 1.95 |
42 | 319.139 | 0.08 | 0.08 | 1.28 |
43 | 492.563 | 0.12 | 0.12 | 1.97 |
44 | 326.345 | 0.08 | 0.08 | 1.31 |
45 | 306.355 | 0.08 | 0.08 | 1.23 |
46 | 284.694 | 1.14 | 0.07 | 18.18 |
47 | 284.694 | 0.28 | 0.07 | 18.18 |
48 | 284.694 | 0.57 | 0.07 | 9.11 |
49 | 250.249 | 1.00 | 1.00 | 1.00 |
50 | 295.246 | 19.23 | 0.15 | 47.06 |
51 | 353.584 | 0.09 | 0.09 | 1.41 |
52 | 353.584 | 0.09 | 0.09 | 1.41 |
53 | 312.747 | 0.08 | 0.08 | 1.25 |
54 | 306.355 | 0.08 | 0.08 | 1.23 |
55 | 445.679 | 735.29 | 446.43 | 1.78 |
56 | 320.339 | 0.16 | 0.08 | 1.28 |
57 | 540.562 | 0.27 | 0.14 | 2.16 |
58 | 580.626 | 0.58 | 0.15 | 2.32 |
60 | 264.276 | 1.05 | 0.07 | 8.46 |
61 | 264.276 | 0.53 | 0.07 | 16.88 |
62 | 295.246 | 1.18 | 0.07 | 1.18 |
63 | 319.139 | 5.10 | 0.08 | 1.28 |