Assessment of the effect of substituents in the phenolic moiety on the relative antimicrobial action of the synthesized compounds.
| Compound | Molar mass (g mol−1) | MIC49/MICcompound | ||
|---|---|---|---|---|
| S. aureus | E. coli | C. albicans | ||
| 34 | 280.275 | 0.07 | 0.28 | 1.12 |
| 35 | 280.275 | 1.12 | 0.07 | 8.97 |
| 36 | 280.275 | 0.14 | 0.07 | 1.12 |
| 37 | 295.246 | 11.79 | 0.07 | 1.18 |
| 38 | 329.145 | 0.33 | 0.08 | 21.05 |
| 39 | 329.145 | 0.08 | 0.08 | 1.32 |
| 40 | 408.041 | 0.10 | 0.10 | 1.63 |
| 41 | 486.937 | 0.12 | 0.12 | 1.95 |
| 42 | 319.139 | 0.08 | 0.08 | 1.28 |
| 43 | 492.563 | 0.12 | 0.12 | 1.97 |
| 44 | 326.345 | 0.08 | 0.08 | 1.31 |
| 45 | 306.355 | 0.08 | 0.08 | 1.23 |
| 46 | 284.694 | 1.14 | 0.07 | 18.18 |
| 47 | 284.694 | 0.28 | 0.07 | 18.18 |
| 48 | 284.694 | 0.57 | 0.07 | 9.11 |
| 49 | 250.249 | 1.00 | 1.00 | 1.00 |
| 50 | 295.246 | 19.23 | 0.15 | 47.06 |
| 51 | 353.584 | 0.09 | 0.09 | 1.41 |
| 52 | 353.584 | 0.09 | 0.09 | 1.41 |
| 53 | 312.747 | 0.08 | 0.08 | 1.25 |
| 54 | 306.355 | 0.08 | 0.08 | 1.23 |
| 55 | 445.679 | 735.29 | 446.43 | 1.78 |
| 56 | 320.339 | 0.16 | 0.08 | 1.28 |
| 57 | 540.562 | 0.27 | 0.14 | 2.16 |
| 58 | 580.626 | 0.58 | 0.15 | 2.32 |
| 60 | 264.276 | 1.05 | 0.07 | 8.46 |
| 61 | 264.276 | 0.53 | 0.07 | 16.88 |
| 62 | 295.246 | 1.18 | 0.07 | 1.18 |
| 63 | 319.139 | 5.10 | 0.08 | 1.28 |