Antimicrobial activity of some monosubstituted 2-aryloxynaphthoquinones at o, m and p positions against S. aureus, E. coli and C. albicans.
Substituent group | MIC (μmol L−1) | ||||||||
---|---|---|---|---|---|---|---|---|---|
S. aureus | E. coli | C. albicans | |||||||
o | m | p | o | m | p | o | m | p | |
–NO2 | 13 | 21.2 | 212 | 1693 | 3387 | 3387 | 85 | 3387 | 3387 |
–Cl | 220 | 878 | 439 | 3512 | 3512 | 3512 | 220 | 220 | 439 |
–OCH3 | 3568 | 223 | 1784 | 892 | 3568 | 3568 | 3568 | 446 | 3568 |