TABLE 3.

Timing, indications, evidence level, and recommendation grade of bone marrow aspiration among children with ITP

Patient group	Clinical feature	Diagnosis and treatment plan	Bone marrow aspiration	Evidence	Recommendation
Newly diagnosed	Typical ITP	Glucocorticoids are unnecessary	Not suggested	III	B
Newly diagnosed	Typical ITP	Glucocorticoids are planned to be dosed	Suggested	III	B
Newly diagnosed	Atypical ITP	To confirm diagnosis and differential diagnosis	Recommended	III	B
Repeated treatment	No response to first‐line treatment	Re‐assessment	Recommended	III	B
Repeated treatment	Persistent or chronic	Re‐assessment	Recommended	IIa	B

Abbreviation: ITP, immune thrombocytopenia.