Table 2. CPT Loading Capacity of the Polymeric Prodrug.
| sample | feed molar ratio of –C≡CH: −N3 | loading capacity (wt %)a |
|---|---|---|
| PEG-g-(PBYP56-ss-CPT) | 5:1 | 8.46 |
| PEG-g-(PBYP56-ss-CPT) | 5:1 | 6.77 |
| cRGD-PEG-g-(PBYP56-ss-CPT) | 5:1 | 16.22 |
| cRGD-PEG-g-(PBYP56-ss-CPT) | 5:1 | 15.43 |
Calculated by CCPT (wt %) = (Ctest/Csample) × 100, where Csample is the concentration of the prodrug and Ctest is UV–vis detected concentration of CPT contained therein.