Table 2. Antiproliferative Evaluation on MDA-MB 231 and Caco-2 Cells.

	IC50a (nM)
compd no.	MDA-MB 231	Caco-2
8a	3.8 ± 0.7	3.3 ± 0.5
8b	81.0 ± 14.3	42.0 ± 1.3
8c	83.7 ± 9.0	26.8 ± 1.3
10	45.0 ± 7.6	54.7 ± 0.5
11	86.6 ± 4.1	64.8 ± 1.3
12	70.9 ± 3.7	52.8 ± 3.8
13	94.4 ± 10.6	38.4 ± 1.6
14a	14.5 ± 1.6	10.2 ± 3.6
14b	79.7 ± 10.2	39.0 ± 1.3
14c	46.7 ± 6.9	39.1 ± 3.1
14d	187.8 ± 8.1	21.5 ± 1.1
14e	72.9 ± 5.3	34.6 ± 0.5
DOX	10.7 ± 0.3	48.3 ± 2.8

^aValues are presented as mean ± SEM.