Table 3. MMPs Inhibitory Profiles of the Selected Dendrimers.
IC50 (nM) |
|||||
---|---|---|---|---|---|
compd no. | MMP-2 | MMP-9 | MMP-7 | MMP-10 | MMP-13 |
8a | 630 | 156 | 200 | 145 | 124 |
14a | 728 | 373 | |||
14b | 98 | 207 | |||
14d | 541 | 243 | |||
NNGH | 77 | 73 | 240 | 101 | 360 |
IC50 (nM) |
|||||
---|---|---|---|---|---|
compd no. | MMP-2 | MMP-9 | MMP-7 | MMP-10 | MMP-13 |
8a | 630 | 156 | 200 | 145 | 124 |
14a | 728 | 373 | |||
14b | 98 | 207 | |||
14d | 541 | 243 | |||
NNGH | 77 | 73 | 240 | 101 | 360 |