Table 2. Cytotoxicity of the Thiazolidine-2,4-Dione Derivatives 4–7 on Human Colon Cancer (Caco-2), Expressed as IC50 (μM).
| compound | IC50 (μM)a |
|---|---|
| 1 | 12.054 ± 3.253 |
| 3a | 74.627 ± 8.310 |
| 3b | 7.028 ± 0.315 |
| 3c | 4.718 ± 0.602 |
| 3d | 8.954 ± 0.631 |
| 3e | 8.478 ± 0.599 |
| 4a | 11.989 ± 1.358 |
| 4b | 13.755 ± 0.789 |
| 4c | 6.517 ± 0.077 |
| 4d | 7.062 ± 0.005 |
| 4e | 12.204 ± 3.124 |
| 5a | 8.201 ± 0.135 |
| 5c | 6.668 ± 0.118 |
| 5d | 8.241 ± 2.589 |
| 5e | 8.571 ± 0.942 |
| 6a | 4.739 ± 0.021 |
| 6c | 10.407 ± 0.499 |
| 6d | 7.940 ± 0.599 |
| 6e | 4.413 ± 0.546 |
| 7a | 10.152 ± 0.770 |
| 7c | 6.765 ± 0.096 |
| 7d | 7.118 ± 0.010 |
| DOX | 19.894 ± 2.370 |
a
All values are expressed as mean ± standard error of mean (SEM).