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. Author manuscript; available in PMC: 2023 Jul 1.
Published in final edited form as: Fertil Steril. 2022 Jul;118(1):148–157. doi: 10.1016/j.fertnstert.2022.03.016

Table 2.

Associations between caffeinated beverages with antral follicle count among 567 women in the EARTH Study.

Servings per day, range n Unadjusted Adjusted mean (95% CI)
Age and total energy Multivariable1

Caffeinated beverages (total)
Q1 (0, 0.45) 141 14.2 (13.6–14.9) 13.7 (13.1–14.4) 13.8 (12.9–14.7)
Q2 (0.46, 1.08) 148 14.1 (13.5–14.7) 13.7 (13.1–14.3) 13.5 (12.7–14.4)
Q3 (1.10, 2.14) 132 14.3 (13.7–15.0) 13.8 (13.2–14.4) 13.9 (13.0–14.7)
Q4 (2.50, 7.08) 146 13.4 (12.8–14.0) 13.7 (13.1–14.4) 13.8 (13.0–14.7)
P-trend 0.04 0.98 0.85
Coffee with caffeine
Q1 (0, 0.02) 140 14.1 (13.5–14.7) 13.6 (13–14.2) 13.5 (12.7–14.4)
Q2 (0.03, 0.43) 167 14.2 (13.7–14.8) 13.9 (13.3–14.5) 14.0 (13.1–14.8)
Q3 (0.8, 1.00) 160 13.9 (13.3–14.5) 13.5 (13.0–14.1) 13.5 (12.7–14.4)
Q4 (2.50, 6.00) 100 13.6 (12.9–14.4) 13.9 (13.2–14.7) 13.9 (13.0–14.9)
P-trend 0.20 0.84 0.81
Decaffeinated coffee
M1/None (0, 0) 307 14.1 (13.7–14.6) 13.7 (13.3–14.1) 13.6 (12.9–14.3)
M2/Any (0.02, 4.50) 260 13.8 (13.4–14.3) 13.8 (13.3–14.2) 13.9 (13.1–14.7)
P-value 0.79 0.79 0.35
Tea with caffeine
T1 (0, 0.03) 207 13.9 (13.4–14.4) 13.6 (13.1–14.1) 13.5 (12.8–14.3)
T2 (0.08, 0.14) 156 15.0 (14.4–15.6)* 14.4 (13.8–15.0)* 14.6 (13.7–15.5)*
T3 (0.43, 6.00) 204 13.3 (12.8–13.8) 13.3 (12.8–13.9) 13.3 (12.6–14.2)
P-trend 0.002 0.08 0.09
Decaffeinated/herbal tea
T1 (0, 0.03) 181 14.1 (13.6–14.6) 13.5 (13.0–14.1) 13.5 (12.7–14.3)
T2 (0.08, 0.14) 158 14.5 (13.9–15.1) 14.2 (13.7–14.8) 14.2 (13.3–15.1)
T3 (0.43, 6.00) 228 13.6 (13.1–14.1) 13.5 (13.1–14.0) 13.7 (12.9–14.5)
P-trend 0.04 0.38 0.73
Caffeinated soda
T1 (0, 0) 283 13.6 (13.1–14.0) 13.5 (13.1–14.0) 13.6 (12.9–14.3)
T2 (0.02, 0.02) 105 14.3 (13.6–15.0) 13.8 (13.1–14.5) 13.9 (13.0–14.9)
T3 (0.04, 4.00) 179 14.5 (14.0–15.1)* 14.0 (13.4–14.5) 13.9 (13.1–14.8)
P-trend 0.01 0.27 0.52
Decaffeinated soda
T1 (0, 0.02) 241 13.4 (12.9–13.8) 13.5 (13.0–13.9) 13.5 (12.8–14.3)
T2 (0.04, 0.08) 133 15.2 (14.6–15.9)* 14.6 (14.0–15.3)* 14.6 (13.7–15.6)*
T3 (0.10, 4.80) 193 14.0 (13.4–14.5) 13.5 (13.0–14.0) 13.5 (12.7–14.3)
P-trend 0.10 0.91 0.80
1

Adjusted for age, body mass index, smoking status, race, physical activity, education, total energy intake, the remaining beverages and the dietary patterns without the specific beverages.

Q: quartiles. T: tertiles. M: median.

*

P <0.05 for comparison of specific category vs category 1 (reference).