Table 2.
Table of pairwise comparisons of baseline power spectra values from 1 to 50 Hz and low gamma frequency band range: (a) pairwise comparisons of baseline power spectra values from 1 to 50 Hz in between NL-G-F and NL-NL animals indicating no significant differences, (b) pairwise comparisons of baseline low gamma power spectra values in animals to be seeded at 6 months of age, NL-G-F and NL-NL animals
| Electrode location | Pairwise comparison | Estimate | SE | df | T ratio | P value |
|---|---|---|---|---|---|---|
| (a) Post hoc pairwise contrasts of 1–50 Hz power spectra values at baseline | ||||||
| Entorhinal area | 3mo NL-G-F-Buffer Pre–3mo NL-NL-Buffer Pre | 0.3187 | 0.1818 | 116 | 1.7527 | 1.2681E−01 |
| 3mo NL-G-F-Tau Pre–3mo NL-NL-Tau Pre | − 0.1970 | 0.1870 | 116 | − 1.0534 | 3.8812E−01 | |
| 6mo NL-G-F-Buffer Pre–6mo NL-NL-Buffer Pre | 0.2375 | 0.1828 | 116 | 1.2996 | 2.7450E−01 | |
| 6mo NL-G-F-Tau Pre–6mo NL-NL-Tau Pre | 0.1870 | 0.1828 | 116 | 1.0230 | 4.0373E−01 | |
| Retrosplenial cortex | 3mo NL-G-F-Buffer Pre–3mo NL-NL-Buffer Pre | 0.0973 | 0.1818 | 116 | 0.5352 | 6.8099E−01 |
| 3mo NL-G-F-Tau Pre–3mo NL-NL-Tau Pre | − 0.1678 | 0.1892 | 116 | − 0.8869 | 4.7571E−01 | |
| 6mo NL-G-F-Buffer Pre–6mo NL-NL-Buffer Pre | 0.0983 | 0.1828 | 116 | 0.5379 | 6.7922E−01 | |
| 6mo NL-G-F-Tau Pre–6mo NL-NL-Tau Pre | − 0.0460 | 0.1850 | 116 | − 0.2487 | 8.5523E−01 | |
| Hippocampal formation | 3mo NL-G-F-Buffer Pre–3mo NL-NL-Buffer Pre | 0.0987 | 0.1818 | 116 | 0.5427 | 6.7634E−01 |
| 3mo NL-G-F-Tau Pre–3mo NL-NL-Tau Pre | 0.2752 | 0.1870 | 116 | 1.4714 | 2.0967E−01 | |
| 6mo NL-G-F-Buffer Pre–6mo NL-NL-Buffer Pre | 0.1285 | 0.1828 | 116 | 0.7032 | 5.8077E−01 | |
| 6mo NL-G-F-Tau Pre–6mo NL-NL-Tau Pre | 0.0568 | 0.1850 | 116 | 0.3072 | 8.2146E−01 | |
| Thalamus | 3mo NL-G-F-Buffer Pre–3mo NL-NL-Buffer Pre | 0.2593 | 0.1818 | 116 | 1.4259 | 2.2588E−01 |
| 3mo NL-G-F-Tau Pre–3mo NL-NL-Tau Pre | 0.1300 | 0.1879 | 116 | 0.6922 | 5.8712E−01 | |
| 6mo NL-G-F-Buffer Pre–6mo NL-NL-Buffer Pre | 0.3864 | 0.1828 | 116 | 2.1145 | 6.0009E−02 | |
| 6mo NL-G-F-Tau Pre–6mo NL-NL-Tau Pre | − 0.0003 | 0.1828 | 116 | − 0.0017 | 9.9916E−01 | |
| (b) Post hoc pairwise contrasts of low gamma power spectra values at baseline | ||||||
| Entorhinal area | 6mo NL-G-F-Buffer Pre–6mo NL-NL-Buffer Pre | − 0.2466 | 0.1116 | 118 | − 2.2094 | 3.8786E−02 |
| 6mo NL-G-F-Tau Pre–6mo NL-NL-Tau Pre | − 0.3409 | 0.1120 | 118 | − 3.0429 | 4.3913E−03 | |
| Retrosplenial cortex | 6mo NL-G-F-Buffer Pre–6mo NL-NL-Tau Pre | − 0.3358 | 0.1266 | 118 | − 2.6521 | 1.3000E−02 |
| 6mo NL-G-F-Tau Pre–6mo NL-NL-Tau Pre | − 0.4319 | 0.1122 | 118 | − 3.8495 | 3.3214E−04 | |
| Hippocampal formation | 6mo NL-G-F-Buffer Pre–6mo NL-NL-Buffer Pre | − 0.4677 | 0.1123 | 118 | − 4.1661 | 1.0783E−04 |
| 6mo NL-G-F-Tau Pre–6mo NL-NL-Tau Pre | − 0.4748 | 0.1129 | 118 | − 4.2070 | 9.2651E−05 | |
| Thalamus | 6mo NL-G-F-Buffer Pre–6mo NL-Buffer Pre | − 0.1635 | 0.1116 | 118 | − 1.4648 | 0.1747 |
| 6mo NL-G-F-Tau Pre–6mo NL-Tau Pre | − 0.4273 | 0.1121 | 118 | − 3.8130 | 0.0004 | |
SE refers to standard error. Df refers to degrees of freedom. Estimate refers to the estimated difference in value between pairwise comparisons. Pre refers to pre-injection recordings