Table 4.
Table of pairwise comparisons of longitudinal phase-amplitude coupling and power spectra differences between buffer and tau-seeded animals: (a) pairwise comparisons of power spectra values of low and high gamma power at 1 and 5 m.p.i. between NL-G-F-tau and NL-G-F-buffer animals at 1 and 5 m.p.i., (b) pairwise comparisons of phase-amplitude coupling of Theta 1-Low Gamma and Theta 2-Low Gamma modulation indices at 5 m.p.i., (c) pairwise comparisons of retrosplenial cortex low gamma power values between NL-G-F-tau and NL-G-F-buffer animals
| Frequency band | Pairwise comparison | estimate | SE | df | T ratio | P value |
|---|---|---|---|---|---|---|
| (a) Post hoc pairwise contrasts of gamma power between NL-G-F-tau and NL-G-F-buffer animals at 1 and 5 m.p.i | ||||||
| Low Gamma | 3mo NL-G-F-Buffer 1mpi–3mo NL-G-F-Tau 1mpi | 2.7109E−01 | 8.6694E−02 | 118 | 3.1270 | 3.4261E−03 |
| 3mo NL-NL-Buffer 1mpi–3mo NL-NL-Tau 1mpi | 3.0630E−01 | 8.7346E−02 | 118 | 3.5068 | 1.0483E−03 | |
| 3mo NL-G-F-Buffer 5mpi–3mo NL-G-F-Tau 5mpi | 3.0341E−01 | 9.8805E−02 | 118 | 3.0708 | 4.0436E−03 | |
| 3mo NL-NL-Buffer 5mpi–3mo NL-NL-Tau 5mpi | 4.0796E−01 | 1.0361E−01 | 118 | 3.9373 | 2.4504E−04 | |
| 6mo NL-G-F-Buffer 5mpi–6mo NL-G-F-Tau 5mpi | 2.9883E−01 | 1.0656E−01 | 118 | 2.8043 | 8.6269E−03 | |
| High Gamma | 3mo NL-G-F-Buffer 1mpi–3mo NL-G-F-Tau 1mpi | 2.3731E−01 | 1.0716E−01 | 116 | 2.2145 | 4.7942E−02 |
| 3mo NL-NL-Buffer 1mpi–3mo NL-NL-Tau 1mpi | 2.9279E−01 | 1.1051E−01 | 116 | 2.6495 | 1.6858E−02 | |
| 3mo NL-G-F-Buffer 5mpi–3mo NL-G-F-Tau 5mpi | 2.9041E−01 | 1.1581E−01 | 116 | 2.5077 | 2.4054E−02 | |
| 3mo NL-NL-Buffer 5mpi–3mo NL-NL-Tau 5mpi | 3.2362E−01 | 1.2555E−01 | 116 | 2.5777 | 2.0239E−02 | |
| 6mo NL-NL-Buffer 1mpi–6mo NL-NL-Tau 1mpi | 2.8866E−01 | 1.0728E−01 | 116 | 2.6906 | 1.5172E−02 | |
| 6mo NL-G-F-Buffer 5mpi–6mo NL-G-F-Tau 5mpi | 2.5549E−01 | 1.0926E−01 | 116 | 2.3384 | 3.6104E−02 | |
| (b) Post hoc pairwise contrasts of hippocampal phase-amplitude coupling modulation indices between NL-G-F-tau and NL-G-F-buffer animals | ||||||
| Theta2-Low Gamma | 3 NL-G-F-Buffer 5mpi–3 NL-G-F-Tau 5mpi | 6.4002E−05 | 2.6238E−05 | 117 | 2.4393 | 3.7753E−02 |
| 6 NL-G-F-Buffer 5mpi–6 NL-G-F-Tau 5mpi | 6.9312E−05 | 2.5494E−05 | 117 | 2.7187 | 1.9664E−02 | |
| Theta1-Low Gamma | 6 NL-G-F-Buffer 5mpi–6 NL-G-F-Tau 5mpi | 2.6314E−05 | 9.8674E−06 | 117 | 2.6668 | 4.0482E−02 |
| (c) Post hoc pairwise contrasts of retrosplenial cortex low gamma power between NL-G-F-buffer and NL-G-F-tau animals | ||||||
| Retrosplenial cortex | 6 NL-G-F-buffer 5mpi–6 NL-G-F Tau 5mpi | 3.8715E−01 | 1.0570E−01 | 118 | 3.6629 | 6.2738E−04 |
Pre refers to pre-injection values, post refers to post-injection values. SE refers to standard error. Df refers to degrees of freedom. Estimate refers to the estimated difference in value between pairwise comparisons