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. 2021 Oct 11;3(4):183–193. doi: 10.1016/j.smhs.2021.09.004

Table 2.

Relationship between sedentary behavior and physical activity with glycemic variability.

Author (publication date) Study design
Number of participants
Primary findings Conclusion Strengths and limitations
Non-diabetic
Gude F et al. (2017)40
Cross-sectional; n ​= ​622
No relationship found between physical activity status with any glycemic variability indices in non-diabetic adults.
Physical activity status may not relate to glycemic variability indices in non-diabetic adults.
Strengths:
Large diverse sample of adults
Limitations:
Cross-sectional design; subjective assessment of physical activity status
Type 1 diabetes
Martyn-Nemeth P et al. (2017)36
Prospective repeated-measures design; n ​= ​35
Total physical activity minutes did not relate to glycemic variability assessed as the SD of the 24-h mean glucose concentration.
Increases in total physical activity performed throughout the day may not relate to lower glycemic variability in type 1 diabetic adults.
Strengths:
Actigraphy-assessed physical activity
Limitations:
Small sample size; physical activity was not a primary outcome of this study
Type 2 diabetes
Paing AC et al. (2018)37 Cross-sectional; n ​= ​37 Sedentary time negatively and breaks in sedentary time positively associated with time spent in euglycemia. Decreasing sedentary time, breaking up sedentary time, or a combination of these sedentary behaviors potentially influence time spent in euglycemia in type 2 diabetic adults. Strengths:
Actigraphy-assessed sedentary time
Limitations:
Cross-sectional design; small sample size
Paing AC et al. (2020)38 Longitudinal; n ​= ​37 Increased sedentary time positively associated with higher glucose concentrations and time spent in-range. Reducing sedentary time and promoting breaks in sedentary time could improve glucose regulation in type 2 diabetes adults. Strengths:
Actigraphy-assessed sedentary time
Limitations:
Cross-sectional design; small sample size
McMillan KA et al. (2020)39 Longitudinal; n ​= ​37 No association between total sedentary time and mean glucose
Sedentary bout duration was positively associated with mean glucose and glucose SD
Sedentary bout duration but not sedentary time was associated with mean glucose and glucose variability. Strengths:
Actigraphy-assessed sedentary time; individual level analysis
Limitations:
Cross-sectional design; small sample size

Table 2 presents studies that provided information regarding the association between sedentary time and physical activity with glycemic control and glycemic variability in non-diabetic, as well as type 1 and type 2 diabetic adults.

The table includes: 1) author information; 2) study design; 3) findings related to the association between sedentary time and physical activity with glycemic control and glycemic variability; 4) conclusions derived from the findings between the relationship between sedentary time and physical activity with glycemic control and glycemic variability; 5) strength and limitations of each study.

SD ​= ​standard deviation; mg/dL ​= ​milligrams per deciliter.