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. Author manuscript; available in PMC: 2022 Jun 23.
Published in final edited form as: Methods Mol Biol. 2022;2419:169–182. doi: 10.1007/978-1-0716-1924-7_10

Table 4.

Monocyte adhesion assay.

Treatment IL-17A LPS + IL-35
Cells HAECs, PBMCs HAECs, PBMCs
Experimental design (trait) Time course Dose response
Result IL-17 significantly increased monocyte adhesion in a time dependent manner and promoted EC activation IL-35 inhibited LPS-induced leukocyte adhesion to ECs in a dose dependent manner
EC status Increases EC activation Inhibits LPS-induced EC activation
PMID 26733204 26085094

EC endothelial cells, HAECs human aortic endothelial cells, IL interleukin, LPS lipopolysaccharide, PBMCs peripheral blood mononuclear cells