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. 2022 Jun 23;12:10648. doi: 10.1038/s41598-022-14743-4

Table 5.

Path coefficients of cross-lagged panel models on PHQ-9 factors and lnRMSSD with covariates.

RMSSD-PHQ-9 som model RMSSD-PHQ-9 cog model
lnRMSSD PHQ-9 som lnRMSSD PHQ-9 cog
Estimate CI Estimate CI Estimate CI Estimate CI
Stability paths (T1–T2) 0.60* 0.53, 0.66 0.62* 0.56, 0.68 0.60* 0.53, 0.66 0.67* 0.61, 0.72
Cross-lagged effects (T1–T2) PHQ-9 som → lnRMSSD lnRMSSD → PHQ-9 som PHQ-9 cog → lnRMSSD lnRMSSD → PHQ-9 cog
− 0.01 − 0.02, 0.01 − 0.19 − 0.49, 0.09 − 0.01 − 0.02, 0.01 0.01 − 0.27, 0.30
Effects of covariates (T1)
Sex 0.03 − 0.05, 0.11 0.09 − 0.23, 0.42 0.03 − 0.05, 0.10 − 0.11 − 0.44, 0.22
Age − 0.01* − 0.01, − 0.01 − 0.01 − 0.02, 0.01 − 0.01* − 0.01, − 0.01 − 0.02* − 0.03, − 0.00
BMI < 0.01 − 0.01, 0.00 0.02 − 0.02, 0.06 < 0.01 − 0.01, 0.00 0.03 − 0.01, 0.06
Smoking − 0.13* − 0.23, − 0.02 − 0.06 − 0.50, 0.37 − 0.13* − 0.23, − 0.03 0.17 − 0.28, 0.62
Alcohol consumption < 0.01 − 0.12, 0.12 − 0.65* − 1.16, − 0.14 < 0.01 − 0.12, 0.11 − 0.19 − 0.73, 0.36
Cardiovascular disease < 0.01 − 0.09, 0.10 − 0.06 − 0.49, 0.35 < 0.01 − 0.10, 0.10 0.15 − 0.28, 0.58

Sex is coded 0 = male, 1 = female; BMI = body mass index; Cardiovascular Disease = self-reported hypertension and/or cardiac arrhythmias; CI = confidence interval; PHQ-9 cog = Patient Health Questionnaire 9—cognitive factor; PHQ-9 som = Patient Health Questionnaire 9—somatic factor; lnRMSSD = root mean square of successive difference between heart beats, logarithmized; T1 = first attended measurement time point; T2 = measurement time point with the largest time-lag to T1.

*CI does not include zero.