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. 2022 Jun 9;13:862709. doi: 10.3389/fphar.2022.862709

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Copyright © 2022 He, Wang, Yang, Ma, Qin, Yan, Rong, Xie, Li, Si, Li and Ma.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Protective effect of Nar against diabetic angiopathies in vivo. (A) HE staining of thoracic aorta from diverse groups of mice. (B) Bar graph of media thickness of aorta in diverse groups. (C) Bar graph of lumen diameter of aorta in diverse groups (D) Bar graph of HE staining analysis the ratio of media thickness/lumen diameter in aorta. ^** p < 0.01, ^*** p < 0.001 compared with Control group, ^# p < 0.05, ^## p < 0.01, ^### p < 0.001, compared with HG group. (E) Representative images of Masson’s staining of the aorta (magnification: 400×).