Table 1. Relationship between CIED-detected AHRE and systemic embolism.
| Trial | Number of patients | Follow-up duration | AHRE duration cut-off | Atrial cut-off rate (bpm) | Hazard ratio for TE event (p-value) |
| Ancillary MOST18 | 312 | 27 months (median) | > 5 min | > 220 | 6.7 (0.020) |
| Italian AT500 registry59 | 725 | 22 months (median) | > 24 h | > 174 | 3.1 (0.044) |
| Botto et al.60 | 568 | 1 year (mean) | CHADS2 and AF burden . 5 min in a day or > 24 h | > 174 | NA |
| TRENDS13 | 2486 | 1.4 years (mean) | ≥ 5.5 h | > 175 | 2.2 (0.060) |
| Home Monitor CRT61 | 560 | 370 days (median) | ≥ 3.8 h | > 180 | 9.4 (0.006) |
| ASSERT49 | 2580 | 2.5 years (mean) | ≥ 6 min | > 190 | 2.5 (0.007) |
| SOS AF53 | 10016 | 2 years (median) | ≥ 1 h | > 175 | 2.11 (0.008) |
| RATE REGISTRY22 | 5379 | 22.9 months (median) | NA | NA | 0.87 (0.51) |