Table 1.
Baseline characteristics of participants with healthy weight and with morbid obesity.
| Healthy weight (n = 21) | Morbid Obesity (n = 21) | P value | |
|---|---|---|---|
| Age (years) | 39.4 (31.3-47.2) | 40.2 (32.2-46.3) | 0.7462 |
| Females, n (%) | 16 (76.2%) | 16 (76.2%) | 1.00 |
| Weight (kg) | 55.4 (49.3- 61.1) | 100 (93.4-114) | < 0.0001 |
| BMI (kg/m2) | 20.6 (19.4-22.5) | 38.5 (35.3-43.3) | < 0.0001 |
| Fat mass (kg) | 17.9 (16.4-21.2) | 48.6 (43.0-52.9) | < 0.0001 |
| Lean body mass (kg) | 35.1 (29.9- 38.1) | 54.2 (44.4-64.6) | < 0.0001 |
| Fat free mass (kg) | 37.6 (32.1- 39.9) | 55.9 (46.5- 67.2) | < 0.0001 |
| Fat mass (%) | 35.1 (28.4- 37.2) | 45.7 (42.1- 50.7) | < 0.0001 |
| Waist circumference (cm) | 76 (74-82) | 117 (112-122) | < 0.0001 |
| Hip circumference (cm) | 94 (90- 98) | 126 (120-134) | < 0.0001 |
| SBP (mmHg) | 112 (102- 118) | 121 (112-139) | 0.0060 |
| DBP (mmHg) | 72 (65-75) | 72 (69-81) | 0.8371 |
| Total cholesterol (mmol/L) | 4.70 (4.12-5.49) | 4.48 (3.85-5.61) | 0.5010 |
| HDL-C (mmol/L) | 1.55 (1.35-1.72) | 1.13 (0.99-1.24) | < 0.0001 |
| Triglyceride (mmol/L) | 0.60 (0.49- 0.90) | 1.47 (1.23-1.81) | < 0.0001 |
| LDL-C (mmol/L) | 2.92 (2.34-3.45) | 2.52 (2.19-3.71) | 0.8276 |
| Creatinine (µmol/L) | 56 (50-67) | 54 (47-62) | 0.4427 |
| Albumin (G/L) | 39 (38-41) | 38 (37-40) | 0.4681 |
| Bilirubin (umol/L) | 13 (11-18) | 11 (10-13) | 0.0413 |
| Alanine transaminase (U/L) | 13 (10-19) | 26 (17-38) | 0.0013 |
| Aspartate transaminase (U/L) | 19 (18-22) | 20 (18-64) | 0.6934 |
| Gamma-glutamyl transferase (U/L) | 13 (12-21) | 28 (24-37) | < 0.001 |
Values are median (inter-quartile range). The Mann–Whitney U test was used to test the statistical differences between participants with healthy weight and with morbid obesity. P value < 0.025 is considered as statistically significant. SBP, systolic blood pressure, DBP, diastolic blood pressure.