Table 3.
Mixed-meal tolerance testing, insulin resistance indices in participants with healthy weight and with morbid obesity.
| Healthy weight (n = 21) | Morbid Obesity (n = 21) | P value | |
|---|---|---|---|
| Fasting glucose (mg/dL) | 87 (85- 89) | 103 (90.7-127) | 0.0017 |
| HbA1C (%) | 5.3 (5.1-5.5) | 5.9 (5.6- 6.2) | < 0.0001 |
| Fasting insulin (mU/L) | 3.2 (2.8-4.7) | 19.5 (13.6- 22.8) | < 0.0001 |
| HOMA-IR | 0.71 (0.55- 1.04) | 4.70 (3.18-5.78) | < 0.0001 |
| Matsuda Index | 9.76 (7.71-12.30) | 1.66 (1.34-2.52) | < 0.0001 |
| Post-MMTT Insulin AUC | 4530 (3840-5230) | 12400 (9130-18200) | < 0.0001 |
| Post-MMTT Glucose AUC | 14500 (13300-17200) | 19400 (16600-21400) | 0.0001 |
Values are median (inter-quartile range). The Mann–Whitney U test was used to test the statistical differences between participants with healthy weight and with morbid obesity. P value < 0.025 is considered as statistically significant. MMTT, mixed-meal tolerance testing, AUC, area under curve.