Table 4.
Plasma concentrations of amino acids in participants with healthy weight and with morbid obesity at baseline.
| (µmol/L) | Healthy weight (n = 21) | Morbid Obesity (n = 21) | P value |
|---|---|---|---|
| Non-essential | |||
| Glycine | 201 (172-227) | 167 (153-172) | 0.0018 |
| Serine | 123 (112-135) | 108 (89.4-120) | 0.0079 |
| Glutamine | 443 (392-449) | 453 (425-523) | 0.1844 |
| Cysteine | 277 (231-300) | 324 (306-362) | 0.0001 |
| Tyrosine | 50.9 (44.6-54.9) | 66.8 (61.5-69.4) | < 0.0001 |
| Arginine | 78.1 (67.5-89.4) | 79.1 (72.8-97.1) | 0.5333 |
| Proline | 129 (104-163) | 148 (132-172) | 0.1530 |
| Alanine | 226 (191-258) | 315 (289-336) | < 0.0001 |
| Asparagine | 35.8 (30.3-37.9) | 34.3 (30.2-38.0) | 0.8813 |
| Aspartate | 1.93 (1.46-2.39) | 2.61 (2.10-3.58) | 0.0052 |
| Glutamate | 26.3 (17.2-34.4) | 50.3 (43.3-73.3) | 0.0003 |
| Essential | |||
| Leucine | 109 (99-116) | 139 (116-146) | 0.0002 |
| Isoleucine | 50.0 (46.9-72.8) | 67.2 (59.6-72.8) | < 0.0001 |
| Valine | 205 (182-229) | 243 (221-288) | 0.0016 |
| Methionine | 18.9 (17.4-21.2) | 21.1 (20.1-24.3) | 0.0028 |
| Phenylalanine | 57.1 (52.7-58.9) | 64.6 (60.2-69.9) | < 0.0001 |
| Threonine | 105 (89-116) | 116 (96.4-134) | 0.1762 |
| Lysine | 161 (144-192) | 195 (176-232) | 0.0004 |
| Histidine | 76.6 (70.7-78.4) | 68.6 (65.7-74.4) | 0.0240 |
| Tryptophan | 38.2 (34.4-41.1) | 39.0 (35.4-43.7) | 0.7088 |
Values are median (inter-quartile range). The Mann–Whitney U test was used to test the statistical differences between participants with healthy weight and with morbid obesity. P value < 0.025 is considered as statistically significant.