Table 2.

Therapy of invasive candidiasis and preferred medications.

Etiologic Agent of Invasive Candidiasis Therapy	C. albicans, C. parapsilosis, C. tropicalis	C. krusei, C. glabrata	C. auris
First-line therapy *	Echinocandin	Echinocandin	Echinocandin
Alternative first-line therapy	Fluconazole	Amphotericin B lipid formulations	Amphotericin B lipid formulations
Step-down therapy **	Fluconazole	Voriconazole	Susceptibility data required

Notes: * Liposomal amphotericin B and flucytosine are used in the central nervous system or for eye infections. ** Step-down therapy is based on MIC assessment in individual cases.