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Improvement of the inflammatory response and recruitment of inflammatory cells due to various factors in the ROCK and PDE family. CyPA: cyclophilin A; ICAM-1: intercellular adhesion molecule 1; MCP-1: monocyte chemoattractant protein 1; NF-κB: nuclear factor kappa-light-chain-enhancer of activated B cells; NO: nitric oxide; PDE-5: phosphodiesterase-5; PKA: protein kinase A; ROCK: rho-associated protein kinase; ROS: reactive oxygen species; VCAM-1: vascular cell adhesion molecule 1.
