Table 1.

Incidence rates of anaphylactic and nonanaphylactic hypersensitivity reactions to COVID-19 vaccines.

Type of Reaction	Number of Participants	Number of Anaphylactic Reactions	Type of Vaccine	Incidence of Reactions (per One Million)	Reference
anaphylactic
	890,604	15	mRNA-1273; BNT162b2	17	[35]
	4,041,396	10	mRNA-1273	37.1	[29]
	1,893,360	21	BNT162b2	11	[36]
	1116	1	BNT162b2; mRNA-1273	890	[37]
	283	5	mRNA-1273 and AZD1222	17,668	[38]
nonanaphylactic
	277	14	BNT162b2	50,540	[39]
	5589	1391	AZD1222 (Astra Zeneca)	248,880	[39]
	5574	6	BNT162b2	1070	[40]
	3170	11	BNT162b2	3470	* [41]
	1,893,360	83	BNT162b2	43.8	* [36]
	877	10	BNT162b2	11,400	[42]
	1116	7	BNT162b2; mRNA-1273	6270	[37]
	74	35	BNT162b2	472,973	[23]

* Nonanaphylactic reactions were classified under skin rashes, including hives, pruritus, and eczematous papules.