Table 2.
Community-onset bacteremia of selected pathogens before and during the COVID-19 pandemic in Hong Kong according to age group a,b.
| From 2012 to 2019 (Period 1) |
From 2020 to 2021 (Period 2) |
p Value | |
|---|---|---|---|
| Patient aged ≤ 12 years | |||
| Streptococcus pyogenes | |||
| Total number of blood cultures | 42 | 0 | |
| Mean (range) blood cultures per year | 5 (1–10) | 0 | NA c |
| Streptococcus pneumoniae | |||
| Total number of blood cultures | 101 | 1 | |
| Mean (range) blood cultures per year | 13 (7–16) | 0.5 (0–1) | <0.001 |
| Haemophilus influenzae | |||
| Total number of blood cultures | 10 | 0 | |
| Mean (range) blood cultures per year | 1 (1–3) | 0 | NA c |
| Methicillin-sensitive Staphylococcus aureus | |||
| Total number of blood cultures | 115 | 24 | |
| Mean (range) blood cultures per year | 14 (11–18) | 12 (9–15) | 0.337 |
| Methicillin-resistant Staphylococcus aureus | |||
| Total number of blood cultures | 15 | 3 | |
| Mean (range) blood cultures per year | 2 (1–3) | 2 (0–3) | 0.755 |
| Escherichia coli | |||
| Total number of blood cultures | 350 | 71 | |
| Mean (range) blood cultures per year | 44 (34–54) | 36 (30–41) | 0.079 |
| Patient aged > 12 years | |||
| Streptococcus pyogenes | |||
| Total number of blood cultures | 544 | 51 | |
| Mean (range) number of blood cultures per year | 68 (37–108) | 26 (21–30) | <0.001 |
| Streptococcus pneumoniae | |||
| Total number of blood cultures | 1125 | 51 | |
| Mean (range) blood cultures per year | 141 (119–175) | 26 (23–28) | <0.001 |
| Haemophilus influenzae | |||
| Total number of blood cultures | 201 | 11 | |
| Mean (range) blood cultures per year | 25 (20–31) | 6 (1–10) | 0.009 |
| Methicillin-sensitive Staphylococcus aureus | |||
| Total number of blood cultures | 5333 | 1483 | |
| Mean (range) blood cultures per year | 667 (564–733) | 742 (704–799) | 0.021 |
| Methicillin-resistant Staphylococcus aureus | |||
| Total number of blood cultures | 3768 | 1064 | |
| Mean (range) blood cultures per year | 471 (394–551) | 532 (515–549) | 0.007 |
| Escherichia coli | |||
| Total number of blood cultures | 45,295 | 12,225 | |
| Mean (range) blood cultures per year | 5662 (4627–6390) |
6113 (6046–6179) |
0.065 |
a Blood culture collected ≤ 2 days after hospital admission. b In light of the limited number of cases, Neisseria meningitidis was not analyzed by age. c p-value not available due to zero cases in period 2.