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Representation of glucose and lactate fluxes through the BBB. Glucose transporters: Glut1 (depicted in green) is expressed in endothelial cells (part of BBB) and in glial cell membrane; Glut3 (yellow) is expressed in neuron membrane. MCT (monocarboxylate transporters family) is depicted in blue: different isoforms (MCT1, MCT2, MCT4) are expressed in endothelial cells (part of the BBB), neurons, astrocytes, and oligodendrocytes.
