Table 4.
Inhibitory ability of S. vulgare crude hydroacetonic extract and purified fractions towards α-amylase and pancreatic lipase activities.
| A-Amylase (IC50, µg/mL) |
Pancreatic Lipase (IC50, µg/mL) |
|
|---|---|---|
| Crude Extract | >400 | >1000 |
| Hex | 45.43 ± 0.22 b | 34.49 ± 1.37 a |
| EtOAc | 42.28 ±5.85 b | 17.98 ± 2.2 b |
| AQ | >400 | >1000 |
| Acarbose | 359.3 ± 8.0 a | -- |
| Orlistat * | -- | 0.06 ± 0.001 c |
* IC50 value for orlistat is expressed in ng/mL. Hex—hexane fraction; EtOAc—ethyl acetate fraction; AQ—aqueous residue. Values are the means of three independent assays ± SD. Means in the same column followed by different letters are significantly different at p < 0.05.