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. 2022 Jun 7;11(6):777. doi: 10.3390/antibiotics11060777

Table 1.

MIC values for meropenem (MEM), cefotaxime (CTX), ceftazidime (CAZ), and resistant genes tested with PCR. MICs indicative of resistance for Enterobacterales, Pseudomonas spp., and Acinetobacter spp. are shown in bold. MICs higher than the meropenem screening breakpoint (ECOFF) are shown in Italics.

Species MIC Values (Lg/mL) bla Genes ampC Genes
MEM CAZ CTX
Enterobacterales
C. freundii 0.016 2 8 TEM-1 CIT
E. agglomerans 0.032 128 512 CTX-M-1, TEM-1
E. coli 4 ≤0.5 ≤0.5 TEM-1
E. coli 0.016 0.5 0.5 TEM-1
E. coli 0.016 8 4 CTX-M-1, TEM-1
E. coli 0.016 32 512 TEM-1, SHV
E. americana 4 32 16 CTX-M-1, TEM-1
Pseudomonas (no breakpoints for CTX)
P. oryzihabitans 256 256 32 TEM-1
Acinetobacter (no breakpoints for CAZ and CTX)
A. lwoffii 0.016 0.5 8 TEM-1
Species with no breakpoints
A. hydrophila 4 32 64 CTX-M-1, TEM-1
A. hydrophila 4 2 0.5 TEM-1
B. cepacia 4 8 16 TEM-1
B. cepacia 8 16 64 CTX-M-1, TEM-1, SHV
B. cepacia 8 16 64 CTX-M-1, TEM-1
C. indologenes 16 512 256 TEM-1
F. odoratum 16 16 64 TEM-1
S. maltophilia 128 64 256 TEM-1
S. maltophilia 64 32 256 TEM-1 EBC
S. maltophilia 64 8 64 TEM-1 EBC
S. maltophilia 64 64 256 TEM-1 ACC
S. maltophilia 64 64 64 TEM-1 CIT
S. maltophilia 64 128 128 CTX-M-1, TEM-1 CIT
S. maltophilia 64 128 256 TEM-1 CIT
S. maltophilia 32 16 256 TEM-1 CIT
S. maltophilia 32 64 256 CTX-M-1, TEM-1 CIT
S. maltophilia 32 128 256 CTX-M-1, TEM-1 CIT
S. maltophilia 32 64 256 CTX-M-1, TEM-1 CIT
S. maltophilia 128 64 256 TEM-1 CIT
S. maltophilia 128 4 64 TEM-1 CIT
S. maltophilia 16 16 64 TEM-1 CIT
S. maltophilia 16 128 512 TEM-1 CIT
S. maltophilia 8 64 128 TEM-1
S. maltophilia 4 2 16 TEM-1 CIT
S. maltophilia 1 2 128 TEM-1