Table 2.
Recommended concentrations for CRKP disinfection according to health industry standards of the People’s Republic of China.
| Iodine | Chlorhexidine | 75% Alcohol |
Quaternary Ammonium Compounds |
3% Hydrogen Peroxide |
Chlorine-Containing Disinfectants | 2% Glutaraldehyde |
||
|---|---|---|---|---|---|---|---|---|
| MBCMAX a | A quarter of stock solution | 2.5 g/L Aqueous chlorhexidine | Half of stock solution | Stock solution (1000 mg/L) | 468.75 mg/L | 1000 mg/L | 0.50% | |
| Skin and mucous membrane b | Skin | Stock solution | ≥ 2 g/L Alcoholic chlorhexidine | Stock solution | Stock solution | |||
| Mucous membrane, wound | ≥ 2 g/L Alcoholic chlorhexidine (wipe), ≥ 2 g/L Aqueous chlorhexidine (rinse, gargle) | 1000–2000 mg/L (wipe) | 3% (flush, gargle) | |||||
| Environmental surface c | Bacterial propagator, mycobacterium tuberculosis, fungus, lipophilic virus | Stock solution | 400–700 mg/L | |||||
| Bacterial propagator, fungus, lipophilic virus | 1000–2000 mg/L | |||||||
| All bacteria (including spores), fungus, virus | 1000–2000 mg/L | 2000–5000 mg/L | ||||||
| Cleaning supplies b | Wash towel | 250 mg/L | ||||||
| Floor towel | 500 mg/L | |||||||
| Flexible endoscope d | ≥ 2% Alkaline solution | |||||||
| Recommended concentration e | ≥2.5 g/L Aqueous chlorhexidine (rinse, gargle) | 1000 mg/L |
Note: a Presents maximum MBC values of seven disinfectants in our study. b Reference to regulation of disinfection technique in healthcare settings. c Reference to regulation for cleaning and disinfection management of environmental surface in healthcare settings. d Referring to regulation for cleaning and disinfection technique of flexible endoscopes. e If MBCMAX is less than or equal to healthcare industry standard requirements, it is marked green; otherwise, it is marked red and listed in accordance with recommended concentrations provided by MBCMAX. MBC, minimum bactericidal concentration.