Table 1.
Participants’ characteristics.
| Measures | 40s (n = 230) |
60s (n = 380) |
T/chi-sq Test (p Value) |
|---|---|---|---|
| Age, years (SD) | 55.77 (1.39) | 75.35 (1.41) | −167.64 (0.000) |
| Education, years (SD) | 14.66 (2.40) | 14.22 (2.67) | 2.08 (0.038) |
| Sex, n (%) | 125 (54.35%) | 169 (44.47%) | 5.21 (0.023) |
| Hypertension, n (%) | 81 (35.22%) | 284 (74.74%) | 91.47 (0.000) |
| Diabetes, n (%) | 12 (5.22%) | 62 (16.32%) | 15.53 (0.000) |
| BMI, kg/m2 (SD) | 27.55 (4.75) | 26.46 (4.79) | 2.76 (0.006) |
| Depression, score (SD) | 2.30 (2.40) | 1.60 (1.77) | 3.85 (0.000) |
| IL1β, pg/mL (SD) | 0.05 (0.09) | 0.04 (0.04) | 2.25 (0.026) |
| IL4, pg/mL (SD) | 0.28 (0.25) | 0.22 (0.18) | 3.06 (0.002) |
| IL6, pg/mL (SD) | 0.69 (2.14) | 0.67 (0.80) | 0.08 (0.933) |
| IL8, pg/mL (SD) | 2.65 (2.26) | 2.90 (2.52) | −1.24 (0.215) |
| IL10, pg/mL (SD) | 0.71 (0.59) | 0.59 (0.53) | 2.37 (0.018) |
| NO, pg/mL (SD) | 14.14 (7.98) | 22.26 (13.13) | −9.50 (0.000) |
| TAC, pg/mL (SD) | 73.24 (18.92) | 64.24 (10.48) | 6.63 (0.000) |
| NEO, pg/mL (SD) | 7.99 (3.75) | 3.01 (2.72) | 17.56 (0.000) |
| MDA, pg/mL (SD) | 84.24 (50.98) | 85.69 (36.51) | −0.38 (0.706) |
| GUA, pg/mL (SD) | 13.43 (5.59) | 12.89 (4.49) | 1.26 (0.210) |
| TNFα, pg/mL (SD) | 2.32 (0.95) | 2.41 (1.34) | −0.92 (0.357) |
| TNFR1, pg/mL (SD) | 1.05 (0.24) | 1.31 (0.49) | −8.78 (0.000) |
| TNFR2, pg/mL (SD) | 1.13 (0.32) | 1.43 (0.54) | −8.85 (0.000) |
| Total tau, pg/mL (SD) | 213.41 (901.67) | 192.92 (751.16) | 0.29 (0.774) |
| Aβ 38, pg/mL (SD) | 206.50 (1142.50) | 138.50 (711.93) | 0.78 (0.433) |
| Aβ 40, pg/mL (SD) | 179.29 (308.42) | 171.78 (164.32) | 0.34 (0.733) |
| Aβ 42, pg/mL (SD) | 25.98 (126.73) | 17.18 (78.55) | 0.95 (0.343) |
| Aβ 40/42 (SD) | 15.13 (5.35) | 17.46 (11.40) | −3.41 (0.001) |